VOLTAMMETRIC DETECTION OF PHOSPHATE ION-BINDING TO BETA-AMINO-CYCLODEXTRIN

The complexation of phosphate ion by beta-amino-cyclodextrin (host 1) was detected by voltammetric methods through the competitive displacem ent of water-soluble ferrocene derivatives from their complexes with h ost 1 in neutral aqueous media. The half-wave potential and the anodic peak current for oxidation of the ferrocene derivative were found to be sensitive to the phosphate concentration throughout a range which i s determined, among other factors, by the concentration of host 1 and the binding constant between the selected ferrocene derivative and the beta-amino-cyclodextrin host.