Patients on a busy obstetric service were prospectively evaluated to d
etermine which ones required blood transfusion. During the period Janu
ary-April 1990, 5,528 deliveries were performed. Fifty-five patients (
0.99%) received blood transfusions during their pregnancy and puerperi
um. The most common conditions associated with transfusion were trauma
due to instrumental delivery (16), uterine atony (15), placenta previ
a (12), retained products of conception (4), abruptio placentae (4) an
d coagulopathy secondary to the HELLP syndrome (1). Platelets, fresh f
rozen plasma, whole blood and cryoprecipitate were administered to 7,
6, 1 and 1 patients, respectively. The transfusion rates by procedure
were emergency cesarean hysterectomy for bleeding placenta previa or a
tony, 7/7 (100%); vacuum extraction, 7/114 (6.1%); forceps delivery, 1
21285 (4.2%); uncomplicated cesarean delivery, 10/704 (1.4%); and spon
taneous vaginal birth, 19/4,425 (0.4%). The hemorrhage and subsequent
need for a blood transfusion were not necessarily due to the procedure
except in the case of trauma due to instrumental vaginal delivery. Th
e rate of transfusion of red blood cells for patients undergoing vagin
al instrumental delivery was significantly higher than the rate for th
ose undergoing cesarean delivery (relative risk, 2.8; 95% confidence i
nterval, 1.5-5.2). The need for transfusion can be anticipated on the
basis of antepartum causes in only 23.7% of patients ultimately receiv
ing blood products.