1,2,4-THIADIAZINO[3,4-B]BENZOTHIAZOLE - A NEW CYCLIC SULPHENIMINE

Authors
JIMONET P AUDIAU F BARREAU M MIGNANI S
Citation
P. Jimonet et al., 1,2,4-THIADIAZINO[3,4-B]BENZOTHIAZOLE - A NEW CYCLIC SULPHENIMINE, Heterocycles, 36(12), 1993, pp. 2745-2752
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
36
Issue
12
Year of publication
1993
Pages
2745 - 2752
Database
ISI
SICI code
0385-5414(1993)36:12<2745:1-ANCS>2.0.ZU;2-U
Abstract
3,4-Dihydro-8-trifluoromethoxy-1,2,4-thiadiazino [3,4-b]benzothiazole (2) was prepared in five steps from 6-trifluoromethoxy-2-benzothiazola mine (riluzole, 1). The key final step consisted of an original N-S bo nd forming reaction between unsubstituted imine and thiol groups, usin g chloramine-T as reagent (75% yield).