Tissue transplantation obviously always involves the risk of HIV trans
mission. Since 1980, the Orthopaedic University of Muenster has conduc
ted careful anamnestic and laboratory screening in 62 donors. Epidemio
logical investigations show that 90.1% of HIV-positive people in Germa
ny are between 20 and 50 years old. For 25 donors (40%) the results of
the HIV antigen test performed in the recipients of the other organs
guaranteed HIV negativity. A further 17 donors (28%) were outside the
epidemiologic risk group aged between 20 and 50 years. Tissue from all
20 other donors (32%) was subjected to a secondary sterilization meth
od, e.g. fumigation with ethylene oxide or irradiation with 25 kGy.