The synthesis of acyclic carbonates of beta-cyclodextrin obtained from
the reaction of alkyloxycarbonylimidazole with beta-cyclodextrin, is
described. The reaction gave a mixture of linear carbonates which were
characterized via TLC, HPLC, C-13 NMR and FT-IR. No cyclic carbonates
have been detected. The products obtained are low-melting, surface ac
tive, easily soluble in water and show good inclusion properties. Thei
r average degree of substitution varies depending on the reaction cond
itions used.