2 CASES OF LONG-TERM DOPAMINE D2 RECEPTOR BLOCKADE AFTER DEPOT NEUROLEPTICS

Authors
HARASKOVANDERMEER C BRUCKE T WENGER S FISCHER P DEECKE L PODREKA I
Citation
C. Haraskovandermeer et al., 2 CASES OF LONG-TERM DOPAMINE D2 RECEPTOR BLOCKADE AFTER DEPOT NEUROLEPTICS, Journal of neural transmission, 94(3), 1993, pp. 217-221
Citations number
8
Categorie Soggetti
Neurosciences
Journal title
Journal of neural transmission → ACNP
ISSN journal
03009564
Volume
94
Issue
3
Year of publication
1993
Pages
217 - 221
Database
ISI
SICI code
0300-9564(1993)94:3<217:2COLDD>2.0.ZU;2-T
Abstract
Two patients with extrapyramidal side effects after the use of fluphen azine decanoate were evaluated by means of IBZM-SPECT. Dopamine D2 rec eptor occupancy 1.5 months after withdrawal still amounted to 83% and 50%. More attention should be focused on long term effects of neurolep tics.