THE VENTILATORY-PERFUSION IMBALANCE IN THE LUNG AFTER BURNS COMPLICATED WITH ACUTE MAJOR BLOOD-LOSS - A DOG STUDY

The study presented investigates indices of central and regional pulmo nary function in dogs after combined trauma (5% full thickness thermal burn with acute blood loss) and during blood transfusion by the intra osteal pumping method. The combined trauma resulted in 100% death of d ogs within the first three hours after the injury. Blood reinfusion ca uses a short-lived beneficial effect. With a relative stabilisation of central hemodynamics pulmonary perfusion decreased to 63% of its init ial value. The lung tissue blood filling increased to 158% with a decr ease of pulmonary air content to 55.8%, this indicated an initial proc ess of liquid blood parts penetrating into the interstitial space and pulmonary alveoli, which resulted in 65% death of dogs.