CHRONIC INTRACTABLE EPILEPSY AS THE ONLY SYMPTOM OF PRIMARY BRAIN-TUMOR

We identified 39 patients with chronic epilepsy (seizures greater than or equal to 2 years) proven to have primary brain tumors. These cases represent similar to 12% of the surgery cases for epilepsy in the sam e period. Mean age of seizure onset was 13.2 years: mean duration befo re operation was 10.5 years. Thirty-eight of 39 had normal neurologic examination. Twenty-six tumors were temporal, 7 were frontal, 4 were p arietal, and 2 were occipital. Nine of 26 (34.6%) of the temporal grou p had contralateral interictal EEG spikes. Pathology was 15 gangliogli oma, 13 low-grade astrocytoma, 4 oligodendroglioma, 2 low-grade mixed glioma, 1 pleomorphic xanthoastrocytoma, 2 dysembryoplastic neuroepith elial tumor, and 1 ependymoma. Postoperative seizure frequency (minimu m follow-up 6 months) ranged from 15 to 16 seizure-free or auras only in patients with temporal tumors and total gross tumor removal (mean f ollow-up 28 months) to 0 of 6 seizure-free in patients with extratempo ral tumors who underwent subtotal resections or biopsy.