B. Dussol et al., ACUTE TRANSPLANT ARTERY THROMBOSIS INDUCED BY ANGIOTENSIN-CONVERTING INHIBITOR IN A PATIENT WITH RENOVASCULAR HYPERTENSION, Nephron, 66(1), 1994, pp. 102-104
Acute renal failure due to angiotensin-converting enzyme inhibitors (A
CEI) usually results from a marked fall in renal perfusion pressure in
patients with renovascular disease. We report herein one case of acut
e kidney transplant artery thrombosis in a patient with renovascular h
ypertension. The thrombosis occurred immediately after a single dose o
f ACEI for evaluation of a renal transplant artery stenosis by renal s
cintigraphy. The dramatic fall of arterial pressure observed in our pa
tient probably played an important role in the thrombosis. The risk of
the administration of a single dose of ACEI coupled with renal scinti
graphy in diagnosing renovascular hypertension is stressed.