INFLUENCE OF INTRAARTICULAR SODIUM HYALURONATE AND POLYSULFATED GLYCOSAMINOGLYCANS ON THE BIOCHEMICAL-COMPOSITION OF EQUINE ARTICULAR SURFACE REPAIR TISSUE

The influence of repeated intra-articular injections of sodium hyaluro nate and polysulphated glycosaminoglycan on the repair of full-thickne ss osteochondral defects was examined in the midcarpal joints of ponie s. The study showed no significant difference between treated and cont rol groups with regard to total collagen content, uronic acid content or the relative proportions of Type I and Type II collagen in the repa ir tissue, indicating that the drugs did not affect the biochemical co mposition of the repair tissue 11 weeks after defect induction.