MALIGNANT ANEUPLOID SPINDLE-CELL TRANSFORMATION IN A PROLIFERATING TRICHILEMMAL TUMOR

A case of spindle-cell carcinoma developed on a proliferating trichile mmal tumour (PTT) is presented. The tumour on the scalp of an 84-year- old white woman was excised and histological examination showed typica l features of PTT, but with a coexistent malignant spindle-cell tumour with a sarcomatoid appearance. There were some areas of transition be tween squamous trichilemmal epithelium and the neoplastic mass compose d of atypical spindle-shaped cells. Two years later, the patient was w ell, and neither recurrence nor metastases were observed. We report th e second case of PTT with a malignant spindle-cell transformation with a sarcomatoid appearance (spindle-cell carcinoma), and a proven aneup loidy, demonstrated with DNA-flow cytometric analysis.