3-PHOSPHONO-1-CARBA-1-DETHIACEPHALOSPORINS AS ANTIBACTERIAL AGENTS

Authors
TERNANSKY RJ PIKE AJ
Citation
Rj. Ternansky et Aj. Pike, 3-PHOSPHONO-1-CARBA-1-DETHIACEPHALOSPORINS AS ANTIBACTERIAL AGENTS, Bioorganic & medicinal chemistry letters, 3(11), 1993, pp. 2237-2240
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
3
Issue
11
Year of publication
1993
Pages
2237 - 2240
Database
ISI
SICI code
0960-894X(1993)3:11<2237:3AAA>2.0.ZU;2-D
Abstract
The synthesis and antibacterial activity of a series of 3-phosphono-1- carba-1-dethiacephalosporins are described. The introduction of phosph orus to the C-3 position of the bicyclic nucleus was accomplished via an Arbuzov-type substitution reaction.