La. Adler et al., VITAMIN-E IN TARDIVE-DYSKINESIA - TIME-COURSE OF EFFECT AFTER PLACEBOSUBSTITUTION, Psychopharmacology bulletin, 29(3), 1993, pp. 371-374
Alpha-tocopherol (vitamin E) has been found to be effective in the tre
atment of tardive dyskinesia (TD). Studies to date have been short in
duration and have not found long-term carryover effects of vitamin E.
The present study examined the persistence of the effects of vitamin E
after longer term (36-week) treatment was discontinued. Vitamin E sig
nificantly improved Tn over this period. However, the effects of vitam
in E persisted so that Tn scores approached baseline only after 12 wee
ks of placebo substitution.