All 79 patients who attended a University Systemic Lupus Erythematosus
(SLE) Clinic over a 6 month period were assessed using the Clinical I
nterview Schedule for psychiatric disorder. Using the ICD-9 Classifica
tion, 40 were found to have psychiatric disorder, 26 having depressive
neurosis, six anxiety neurosis, five endogenous depression and three
dementia. The group with psychiatric disorder had significantly poor f
amily support as well as lack of a confidant compared to the group wit
hout psychiatric disorder (P < 0.01). There was no difference between
the group with psychiatric disorder and those without psychiatric diso
rder in terms of age, duration of illness, ethnicity and severity of S
LE. Psychiatric disorder is common affecting more than half the subjec
ts and depression was the most frequent diagnosis.