REACTIONS OF 4 6-AMIDE-LACTAME FUNCTION O F NUCLEIC BASES/

Citation
Mo. Taktakishvili, REACTIONS OF 4 6-AMIDE-LACTAME FUNCTION O F NUCLEIC BASES/, Bioorganiceskaa himia, 19(11), 1993, pp. 1029-1064
Citations number
161
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
01323423
Volume
19
Issue
11
Year of publication
1993
Pages
1029 - 1064
Database
ISI
SICI code
0132-3423(1993)19:11<1029:RO46FO>2.0.ZU;2-0
Abstract
Reactivity of the amide-lactame function of nucleic bases under variou s conditions, methods of its activation, protection, deprotection and modification have been considered. Expediency of the function's protec tion in oligonucleotide synthesis is discussed.