ANTICHOLINESTERASE ACTIVITY OF CARBORANYL CONTAINING THIOESTER AND SELENOESTER OF PENTAVALENT PHOSPHORUS-ACIDS

Authors
BALEMA VP RYS EG SOCHILINA EE YAGODINA OV MORALEV SN ZHUKOVSKY YG GODOVIKOV NN KABACHNIK MI
Citation
Vp. Balema et al., ANTICHOLINESTERASE ACTIVITY OF CARBORANYL CONTAINING THIOESTER AND SELENOESTER OF PENTAVALENT PHOSPHORUS-ACIDS, Bioorganiceskaa himia, 19(11), 1993, pp. 1077-1080
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Bioorganiceskaa himia → ACNP
ISSN journal
01323423
Volume
19
Issue
11
Year of publication
1993
Pages
1077 - 1080
Database
ISI
SICI code
0132-3423(1993)19:11<1077:AAOCCT>2.0.ZU;2-X
Abstract
Anticholinesterase activity of carboranyl containing thio- and selenoe sters of pentavalent phosphorus acids has been studied. Insertion of t he carboranyl substituents in the thioester group of phosphororganic c ompounds was found to increase the anticholinesterase activity as comp ared with the thioalkyl analogues. The compounds with B-carboranyl gro up are less active inhibitors of cholinesterase than their isomers wit h C-carboranyl group.