J. Siegert et al., RADICAL EXCISION OF THE CONJUNCTIVA IN TH E THERAPY OF MALIGNANT-MELANOMA OF THE CONJUNCTIVA, Klinische Monatsblatter fur Augenheilkunde, 203(6), 1993, pp. 413-417
Background In tumor excision of large malignant melanomas of the conju
nctiva or in the excision of widespread precancerous melanosis the dev
elopment of symblepharon is a threatening complication after conjuncti
vectomy, especially if the conjunctival fornix is afflicted. Patients
Three patients with suspected nodular melanoma and surrounding precanc
erous melanosis of the conjunctiva were treated by extended excision o
f the conjunctiva. Instead of a conjunctival graft, spontaneous epithe
lisation under the protection of an 'Illig' contact lens was achieved.
After this, two patients with histologically proven malignant melanom
as were treated by beta-ray radiation with 90-Strontium. Results Withi
n four weeks after the excision a complete epithelisation of the wound
occurred and the functional as well as the cosmetic results were very
satisfying. During the follow-up between 12 and 22 months no recurren
ce of the melanomas and no formation of symblepharon was observed. Con
clusions With regard to these results extended tumor excision without
conjunctival graft seems to be a reasonable therapy for large nodular
melanomas and widespread melanosis, while the application of an 'Illig
' contact lens avoids the formation of symblepharon.