THE IN-VITRO EFFECTS OF CEFTIBUTEN ON THE HOST-DEFENSE MECHANISM

Authors
BRAGA PC PIATTI G DALSASSO M MACI S BLASI F
Citation
Pc. Braga et al., THE IN-VITRO EFFECTS OF CEFTIBUTEN ON THE HOST-DEFENSE MECHANISM, Chemotherapy, 40(1), 1994, pp. 37-41
Citations number
17
Categorie Soggetti
Pharmacology & Pharmacy",Oncology
Journal title
Chemotherapy → ACNP
ISSN journal
00093157
Volume
40
Issue
1
Year of publication
1994
Pages
37 - 41
Database
ISI
SICI code
0009-3157(1994)40:1<37:TIEOCO>2.0.ZU;2-#
Abstract
The in vitro effects of ceftibuten on human polymorphonuclear leukocyt e (PMN) chemotaxis, phagocytosis and chemiluminescence were investigat ed. PMN from healthy adult donors were incubated for 1 h in medium alo ne or in medium containing increasing concentrations of ceftibuten (4, 8 and 40 times the MIC for Escherichia coli). Up to 40 MIC ceftibuten did not significantly interfere with the function of PMN.