Most surgeons consider patients with solitary adrenal metastasis from
a primary lung carcinoma incurable and avoid excision of both the adre
nal and primary lung tumors. However, several cases of successful surg
ical management of these patients recently have been reported. We revi
ewed 12 surgically treated patients with isolated adrenal and lung dis
ease and identified 2 survivors of greater than fifteen years (17%) an
d 4 additional patients who are still alive following combined resecti
on (34%). This survival rate, albeit in a selected population, represe
nts an improvement over the natural history of nine months' survival.
We suggest that if after six to twelve months of following patients wi
th lung cancer and isolated adrenal metastasis no other evidence of sp
read of disease is evident, the tumor biology may be favorable and res
ection of both adrenal and lung lesions is reasonable.