COMBINED TREATMENT OF STABLE ANGINA-PECTO RIS WITH TRINITROLONG COMBINED WITH PROPRANOLOL

Trinitrolong (TNL), a long-acting nitroglycerin for application on the gingiva, was comparatively assessed for effect on stable angina pecto ris in monotherapy and in combination with beta-adrenoblocker proprano lol. A total of 11 anginal patients received the combination the effic acy of which was verified by paired bicycle ergometry. A high antiangi nal effect of TNL was established. However, its combination with propr anolol entails neither higher exercise tolerance nor less frequent ang inal attacks. An increment in the effect was not seen either when the combination was used in single and course doses in one-third of the pa tients.