Regularities in the development of anemia in patients with chronic hep
atitis or hepatocirrhosis were studied with regard to the pattern and
stage of the affection of the liver. The impact of inefficient erythro
poiesis on anemia development in patients with chronic diffuse disease
s of the liver was demonstrated. Reasons of the red cells imperfection
that caused their rapid hemolysis were indicated. In the bone marrow
of chronically ill patients there were lower levels of early precursor
s of erythropoiesis with their proliferative activity reduced. On the
basis of the data obtained the authors gave practical recommendations
for anemia treatment.