Mbm. Ruijs et al., SOMATOSENSORY-EVOKED POTENTIALS AND COGNITIVE SEQUELAE IN CHILDREN WITH CLOSED HEAD-INJURY, Neuropediatrics, 24(6), 1993, pp. 307-312
In search of a prognostic indicator for residual cognitive function lo
ss in children after closed head-injury, the somatosensory evoked pote
ntial P300 has been studied in a prospective follow-up study of 17 pat
ients with mild and moderately severe head-injuries. The P300 response
was measured in the acute phase after patients regained consciousness
. In addition the duration of coma and of post-traumatic amnesia were
recorded. An age-matched control group of 20 healthy children supplied
age-related normative evoked potential data. During a two-years follo
w-up period the presence of residual disorders in various faculties wa
s evaluated at fixed time intervals after discharge. Correlation analy
ses revealed that, where the duration of coma and of post-traumatic am
nesia qualify as general predictors of sequelae, the long-latency soma
tosensory evoked potential P300 correlated specifically with long-term
deficits in the field of school performance.