The argon beam coagulator is a new device for haemostasis during and a
fter surgery on parenchymatous organs. No data are available on its ef
ficacy and tissue effect following hepatic resection. Blood loss, the
time needed to achieve adequate haemostasis and histological findings
after liver resection were assessed in 12 pigs using argon beam coagul
ation or suture ligation only, the mattress suture technique and tissu
e glue application. The treatment was randomly assigned to each of the
four liver lobes in each pig. Median blood loss following argon beam
coagulation was 13 (range 2-47) mi and after simple suture ligation 55
(range 2-260) ml(P<0.02). The median time needed for adequate haemost
asis following argon beam coagulation was 3 (range 2-7) min versus 14
(range 2-48) min in the control group (P<0.005). There was no differen
ce between argon beam coagulation and tissue glue, which were both sup
erior to the use of mattress sutures. Argon beam coagulation resulted
in less tissue damage than tissue glue or mattress suturing. The argon
beam coagulator is an efficient device for achieving haemostasis foll
owing partial hepatectomy in the pig. rt causes only a moderate tissue
reaction.