We report the analysis of the biases of CpG, TpG, and CpA of all the D
NA sequences data from the Trematode Schistosoma mansoni. Our results
show CpG avoidance whereas TpG and CpA frequencies are over the expect
ed values. These characteristics are similar to the biases displayed b
y methylated genomes, but in platyhelminths 5mC has not been detected
by biochemical methods. The possible implications of this CpG shortage
are discussed.