This study was carried out to develop and test the Geriatric Quality o
f Life Questionnaire (GQLQ), a health-related qualify of life (HRQL) q
uestionnaire designed for the frail elderly. One hundred patients were
asked to identify areas of their daily lives affected by their health
. The GQLQ, developed on the basis of the results, the Rand Physical a
nd Emotional Function Questionnaires, and the Barthel Index, were admi
nistered serially to a group of 76 patients participating in a randomi
zed trial of a Geriatric Day Hospital. Participants in all phases of t
he study were over 65 years of age, living in their own home but with
sufficient functional status impairment to compromise their ability to
live independently. The GQLQ includes 25 questions focusing on activi
ties of daily living (ADL), symptoms, and emotional function. In the A
DL and Symptom domains respondents define personal problem areas. The
responsiveness coefficients of the GQLQ ADL and Symptom domains (0.26
and 0.30 respectively) were similar to those of the Rand Physical Func
tion instrument and the Barthel Index (0.29 and 0.20). The responsiven
ess coefficient of the GQLQ Emotional Function domain (0.50) was simil
ar to that of the Rand Emotional Function instrument (0.63). Correlati
ons between the GQLQ ADL domain and the Barthel Index (0.41), and betw
een GQLQ and the Rand Physical Function instrument (0.30), were simila
r to the correlation between the Barthel Index and Rand Physical Funct
ion (0.40). While the GQLQ captures important areas of health-related
quality of life impairment for the frail elderly, we failed to show an
y advantages in either responsiveness or validity to existing, simpler
measures. New, specific instruments should be tested in head-to-head
comparisons with existing measures, particularly generic instruments,
before dissemination.