T. Korenaga et al., COMPUTER-CONTROLLED MICROPUMP SUITABLE FOR PRECISE MICROLITER DELIVERY AND COMPLETE IN-LINE MIXING, Analytical chemistry, 66(1), 1994, pp. 73-78
A novel computer-controlled micropump is developed for various flow an
alyses and offers a number of improvements to the limitations of conve
ntional pumping systems. With flow patterns which are easily programme
d, the pump allows precise microliter delivery and complete in-line mi
xing to be conveniently achieved. This instrument is particularly suit
able for both heterogeneous flow analysis and flow analysis based on s
low reaction because it provides a large interface between immiscible
phases or miscible streams just after merging and hence promotes mas t
ransfer in radial directions. The improvement of radial mass transfer
results in a complete reaction and high sensitivity with limited dispe
rsion volume of the sample. The mechanical stability and reproducibili
ty of this pump is excellent, allowing it to be applied successfully i
n process analysis over long periods of time.