Objective: To test the effects of a skin protectant - surgical scrub a
nd glove integrity. Design: Forty-nine healthy adult volunteers were a
ssigned (12 subjects per group) to apply a protective foam (DermaMed;
Benchmark Enterprises, Salt Lake City, Utah) in conjunction with surgi
cal scrub in one of the following formulations: 70% isopropyl alcohol,
a liquid detergent base containing 4% chlorhexidine gluconate, a liqu
id detergent base containing 7.5% povidone-iodine, or a nonantimicrobi
al liquid soap (control). According to a standard protocol, subjects p
erformed a surgical scrub on 3 days (every other day). Foam was applie
d after surgical scrub on day 1 and before surgical scrub on day 3. No
foam was applied on day 2. Subjects were gloved for 2 hours after sur
gical scrub. Setting: Laboratory setting. Results: On all test days, t
here were significant differences in bacterial reduction by products (
chlorhexidine gluconate or alcohol > povidone-iodine > control). When
controlling for baseline counts and products used, there were no signi
ficant differences in colony-forming unit counts on hands with or with
out foam immediately after scrubbing or at 2 hours after scrub on glov
ed or ungloved hands, nor were there differences in glove leakage rate
s when foam was on hands. Conclusions: Such protectants can be used wi
thout detrimental effects to scrub effectiveness or glove integrity.