FREQUENCY OF SEAFOOD INTAKE IN PREGNANCY AS A DETERMINANT OF BIRTH-WEIGHT - EVIDENCE FOR A DOSE-DEPENDENT RELATIONSHIP

Study objective-The aim was to explore whether maternal consumption of seafood is a determinant of birth weight in a dose dependent manner. Design-A population based survey of life-style factors in pregnancy wa s linked with information from antenatal and obstetric records. Settin g and participants-Seventy five per cent of all 1362 women who deliver ed in the Faroe Islands during the study period 1986-87 who gave a str uctured post partum interview on lifestyle factors. Main results-Altog ether, 2, 6, 16, 33, 26, 14, and 3% of women had consumed approximatel y 0, 1, 2, 3, 4, 5, and 6+ respectively seafood (fish or whale) dinner meals per week during pregnancy. The average birth weight (p=0.02) an d birth length (p=0.002) varied significantly between the seven groups , and increased by about 0.2 kg and 1 cm, respectively between women w ho ate 0 and those who consumed 3 seafood meals per week. Mean birth w eight and length tended to level off with further fish consumption: wh en fitting a second degree polynomial, the quadratic terms were negati ve and significant for both birth weight (p=0.005) and length (p=0.001 ). Analogous analyses for pregnancy duration were not significant, but exhibited similar trends. All analyses were adjusted for maternal hei ght, weight, parity, age, marital status, and smoking. Conclusions-The weight and length of the newborn increased with the frequency of seaf ood dinner meals consumed in pregnancy but only up to a consumption le vel of about 3 meals per week.