Patients with chronic bronchitis for whom major elective surgery is in
dicated are at increased risk for perioperative respiratory complicati
ons. The principal clinical features of chronic bronchitis, including
excessive mucus Secretion, productive cough, and respiratory infection
, are related to a persistent inflammatory insult. The insult provokes
mucus hypersecretion, obstruction to airflow, and paralysis of airway
defense mechanisms. A comprehensive preoperative medical regimen that
reduces inflammation, clears and reduces mucus secretions, treats und
erlying infection, ameliorates inflammation, and increases airway cali
ber ensures the best surgical outcome.