K. Willi et al., TEMPERATE BACTERIOPHAGES ACTINOBACILLUS-ACTINOMYCETEMCOMITANS ASSOCIATED WITH PERIODONTAL-DISEASE ARE GENETICALLY RELATED, Medical microbiology letters, 2(8), 1993, pp. 419-426
Five bacteriophages of Actinobacillus actinomycetemcomitans isolated f
rom periodontal pockets in three European countries are genetically hi
ghly related: they have the same virion structure, and the DNA genomes
show identical or similar restriction fragment patterns and extensive
DNA homology. However, they form two immunity groups. Their hosts bel
ong to two genotypes. The significance with respect to pathogenesis an
d diagnostics is discussed.