Powder of a dental plaster (Moldabaster(R), Bayer) was compacted by co
ld isostatic pressing (CIP) at 300 MPa for 10 min and immersed in wate
r for 1 h. The compressive strength of the CIP-processed material was
compared with that of conventionally processed material. The green blo
ck of plaster before water immersion was carvable with a green density
and green strength of 50% and 5 MPa, respectively. The compressive st
rength of the CIP-processed gypsum after 24 h was three times higher t
han that of conventionally processed, 103 compared with 29 MPa, and th
e microhardness (Vickers hardness number, VHN) of CIP-processed materi
als was 40 compared with 12VHN. An increase of density was also record
ed. It seems that the CIP process produced a dense and pore-free gypsu
m with a composite-like structure. The high-strength gypsum processed
by CIP may extend the applications of this material in the medical fie
ld as implant materials.