J. Pierart et al., CAUSES OF INCREASING PERICARDIAL PRESSURE IN EXPERIMENTAL CARDIAC-TAMPONADE INDUCED BY VENTRICULAR PERFORATION, The journal of trauma, injury, infection, and critical care, 35(6), 1993, pp. 834-836
It has been shown that the intravenous infusion of saline solution in
a dog with stabilized cardiac tamponade produced an increase in perica
rdial pressure. To demonstrate that this pressure increase is the resu
lt of bleeding into the pericardial sac, an experimental study was con
ducted, consisting of the injection of red cells marked with Cr-51 dur
ing the intravenous infusion of saline solution in dogs with and witho
ut progressive tamponade. The results showed that in the dogs without
progressive tamponade, both the pericardial pressure and the red cell
count in the pericardial cavity remained stable during the infusion of
saline solution, whereas in dogs with progressive tamponade, the numb
ers of marked cells and the pericardial pressure increased significant
ly, following a similar pattern.