STABILITY OF DNA FINGERPRINT PATTERN PRODUCED WITH IS6110 IN STRAINS OF MYCOBACTERIUM-TUBERCULOSIS

Authors
CAVE MD EISENACH KD TEMPLETON G SALFINGER M MAZUREK G BATES JH CRAWFORD JT
Citation
Md. Cave et al., STABILITY OF DNA FINGERPRINT PATTERN PRODUCED WITH IS6110 IN STRAINS OF MYCOBACTERIUM-TUBERCULOSIS, Journal of clinical microbiology, 32(1), 1994, pp. 262-266
Citations number
17
Categorie Soggetti
Microbiology
Journal title
Journal of clinical microbiology → ACNP
ISSN journal
00951137
Volume
32
Issue
1
Year of publication
1994
Pages
262 - 266
Database
ISI
SICI code
0095-1137(1994)32:1<262:SODFPP>2.0.ZU;2-D
Abstract
To assess the stability of IS6110 restriction fragment length polymorp hism patterns, DNA fingerprints of 6 Mycobacterium bovis isolates from 1 patient and of 41 Mycobacterium tuberculosis isolates from 18 patie nts were compared. The fingerprint pattern for a given patient remaine d identical or nearly identical despite recovery of the isolates durin g intervals which ranged from 8 months to 4.5 years. Changes in drug r esistance profile did not alter a strain's fingerprint pattern.