PREGNANCY IN RENAL-TRANSPLANT RECIPIENTS

11 women gave birth to 13 live-born infants after a mean period of 39. 6 months following transplantation, whereby one of these women had two successfull pregnancies and one patient had a twin pregnancy. The hig hly premature twins, born after a complicated pregnancy with impaired renal graft Function in the mother, died of respiratory insufficiency on the 13th day. All of these renal allograft recipients had to be del ivered by caesarean section, either for nephrological or obstetric rea sons. All graft with stable function prior to conception suffered no d amage as a result of the pregnancy. In two women with already impaired function, pregnancy led to further deterioration and, eventually, gra ft loss. Because of the small numbers in this series no conclusions ca n be drawn with regard to the incidence of malformation of premature d elivery. It is concluded that women with normal and stable renal graft function should be allowed to become pregnant. The risk for the graft as well as for the child does not seem to be increased under these ci rcumstances. However, due to the complexity of the situation these pat ients should be cared for at specialized centres.