M. Vonflue et al., PORTAL-VEIN THROMBOSIS FOLLOWING SPLENECT OMY IN PORTAL-HYPERTENSION - RISKS AND MANAGEMENT, Schweizerische medizinische Wochenschrift, 123(49), 1993, pp. 2309-2317
Splenectomy intended to treat hypersplenism can, in the presence of po
rtal hypertension (PTH), lead to extrahepatic portal and mesenteric ve
in thrombosis. The management of possible variceal bleeding in patient
s with extrahepatic portal vein occlusion following splenectomy in por
tal hypertension is a problematic and challenging undertaking. We repo
rt on the management of variceal bleeding in 2 noncirrhotic patients w
ith PTH who developed portal vein thrombosis following ill-advised spl
enectomy.It must be stressed again that splenectomy alone intended to
control hypersplenism in portal hypertension is to be avoided at all c
osts. Options for the treatment of portal and mesenteric vein thrombos
is and variceal bleeding are proposed.