STRUCTURE AND FUNCTION OF THE BACTERIOPHAGE-T7 RNA-POLYMERASE (OR, THE VIRTUES OF SIMPLICITY)

Authors
MCALLISTER WT
Citation
Wt. Mcallister, STRUCTURE AND FUNCTION OF THE BACTERIOPHAGE-T7 RNA-POLYMERASE (OR, THE VIRTUES OF SIMPLICITY), Cellular & molecular biology research, 39(4), 1993, pp. 385-391
Citations number
32
Categorie Soggetti
Cytology & Histology",Biology
Journal title
Cellular & molecular biology research → ACNP
ISSN journal
09688773
Volume
39
Issue
4
Year of publication
1993
Pages
385 - 391
Database
ISI
SICI code
0968-8773(1993)39:4<385:SAFOTB>2.0.ZU;2-G
Abstract
A consideration of the properties of a number of mutants of T7 RNA pol ymerase, together with emerging structural information (Sousa et al., 1993) allows an interpretation of the the mechanics of transcription b y this relatively simple RNA polymerase. Evidence indicating features in common with other nucleotide polymerases (such as DNA polymerases a nd reverse transcriptases) is reviewed.