BIOACTIVE COMPOUNDS FROM THE BUDS OF PLATANUS-ORIENTALIS AND ISOLATION OF A NEW KAEMPFEROL GLYCOSIDE

A new compound kaempferol 3-O-alpha-L-(2''-E-p-coumaroyl)-rhamnopyrano side, as well as the known flavonoids, kaempferol 3-O-beta-D-(6''-E-p- coumaroyl)-glucopyranoside, kaempferol pha-L-(2'',3''-di-E-p-coumaroyl )-rhamnopyranoside, and caffeic acid were obtained from the methanolic extract of Platanus orientalis L. buds. All the compounds were isolat ed by column chromatography and identified using H-1-NMR, 2D-H-1-NMR ( COSY), H-1-C-13-NMR, and CIDMS techniques. Cytotoxic and antimicrobial studies were carried out in vitro against human cell lines and agains t Gram-positive and Gram-negative organisms.