I. Ikarashi et al., EFFECT OF NEONATAL GONADECTOMY ON LYMPHOCYTES POPULATION AND BLAST FORMATION IN AGED RATS, Journal of veterinary medical science, 55(6), 1993, pp. 1077-1079
In male rats gonadectomized at birth, the blast formation reaction of
lymphocytes was significantly lower at 114 weeks of age, than that of
non-gonadectomized controls, whereas the lymphocyte subpopulation was
similar. The thymus of neonatally castrated rats of age 114 weeks was
histologically normal, decreasing in weight to 68% of that of non-cast
rated rats.