Acute disseminated encephalomyelitis (ADEM) is a rare demyelinating co
ndition of the central nervous system, usually developing after a vira
l infection or vaccination. We report a case of ADEM predominantly aff
ecting the spinal cord in an 8-year old boy evaluated by MRI. The radi
ographic picture consisted of multiple focal lesions of the spinal cor
d, a left posterior thalamic lesion and a subcortical right posterior
parietal lesion. These lesions regressed several weeks after corticost
eroid treatment. The clinical presentation, the laboratory results and
the radiological findings suggest the diagnosis of ADEM secondary to
viral infection by Coxsackie B.