Re. Markwell et al., SYNTHESIS OF AMINOAZALACTAMS AS CYCLIC MIMETICS OF BASIC ALKYL AMINO-ACIDS, Bioorganic & medicinal chemistry letters, 3(12), 1993, pp. 2537-2540
Novel medium ring conformationally constrained amino acid derivatives
2 for incorporation into collagenase inhibitors were prepared, utilisi
ng natural amino acids as starting materials, via a reductive intramol
ecular imine cyclisation.