SYNTHESIS, BIOLOGICAL PROPERTIES, AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF QUINOXALINE ANGIOTENSIN-II RECEPTOR ANTAGONISTS

Authors
KIM KS QIAN L DICKINSON KEJ DELANEY CL BIRD JE WALDRON TL MORELAND S
Citation
Ks. Kim et al., SYNTHESIS, BIOLOGICAL PROPERTIES, AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF QUINOXALINE ANGIOTENSIN-II RECEPTOR ANTAGONISTS, Bioorganic & medicinal chemistry letters, 3(12), 1993, pp. 2667-2670
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
3
Issue
12
Year of publication
1993
Pages
2667 - 2670
Database
ISI
SICI code
0960-894X(1993)3:12<2667:SBPAS>2.0.ZU;2-N
Abstract
Quinoxaline heterocycle containing angiotensin II receptor antagonist analogs were prepared. All five analogs reported here display potent a ntagonistic activities and most interestingly, quinoxaline bis-N-oxide 10 exhibits very potent activities both in binding and functional ass ays.