PHENYLACETYL GROUP AS ENZYME-CLEAVABLE AMINOPROTECTION OF PURINE NUCLEOSIDES

Authors
DINEVA MA GALUNSKY B KASCHE V PETKOV DD
Citation
Ma. Dineva et al., PHENYLACETYL GROUP AS ENZYME-CLEAVABLE AMINOPROTECTION OF PURINE NUCLEOSIDES, Bioorganic & medicinal chemistry letters, 3(12), 1993, pp. 2781-2784
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
3
Issue
12
Year of publication
1993
Pages
2781 - 2784
Database
ISI
SICI code
0960-894X(1993)3:12<2781:PGAEAO>2.0.ZU;2-A
Abstract
N6-Phenylacetyl-2'-deoxyadenosine and N2-Phenylacetyl-2'-deoxyguanosin e are readily deprotected in reactions catalyzed by free and immobiliz ed penicillin amidase at pH 7.8 and 25-degrees-C.