SYNTHESIS AND IN-VITRO ACETYLCHOLINESTERASE INHIBITORY ACTIVITY OF SOME 1-SUBSTITUTED ANALOGS OF VELNACRINE

Authors
KAPPLES KJ SHUTSKE GM BORES GM HUGER FP
Citation
Kj. Kapples et al., SYNTHESIS AND IN-VITRO ACETYLCHOLINESTERASE INHIBITORY ACTIVITY OF SOME 1-SUBSTITUTED ANALOGS OF VELNACRINE, Bioorganic & medicinal chemistry letters, 3(12), 1993, pp. 2789-2792
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
3
Issue
12
Year of publication
1993
Pages
2789 - 2792
Database
ISI
SICI code
0960-894X(1993)3:12<2789:SAIAIA>2.0.ZU;2-I
Abstract
A number of analogues of 9-amino-1,2,3,4-tetrahydro-1-acridinol (velna crine), with 1-position substituents other than hydroxy, were prepared and evaluated for in vitro acetylcholinesterase inhibition.