INDOCYANINE GREEN ANGIOGRAPHY IN MULTIPLE EVANESCENT WHITE-DOT SYNDROME

Using indocyanine green angiography we examined two patients with mult iple evanescent white-dot syndrome. Both patients had unilateral loss of vision and a fundus appearance typical of multiple evanescent white -dot syndrome. Fluorescein angiography in both patients disclosed a pa tchy hyperfluorescent pattern at the level of the retinal pigment epit helium. Using indocyanine green angiography, we observed multiple deep , small, round hypofluorescent lesions that appeared early and persist ed into the late phases. The spots appeared to block the underlying ch oroidal pattern. These hypofluorescent spots were clearly visible and present throughout the posterior pole. Many more spots were seen on in docyanine green angiography than were visible by clinical examination or angiography. After follow-up examinations, there was a rapid resolu tion of the spots over four to six weeks with return of vision. Our fi ndings show that indocyanine green angiography can be a valuable tool in the recognition and further understanding of multiple evanescent wh ite-dot syndrome.