SYNTHESIS OF OLIGOSACCHARIDES WITH OLIGOETHYLENE GLYCOL SPACERS AND THEIR CONVERSION INTO GLYCOCONJUGATES USING N,N,N',N'-TETRAMETHYL(SUCCINIMIDO)URONIUM TETRAFLUOROBORATE AS COUPLING REAGENT (VOL 10, PG 197, 1993)

Authors
ANDERSSON M OSCARSON S OHBERG L
Citation
M. Andersson et al., SYNTHESIS OF OLIGOSACCHARIDES WITH OLIGOETHYLENE GLYCOL SPACERS AND THEIR CONVERSION INTO GLYCOCONJUGATES USING N,N,N',N'-TETRAMETHYL(SUCCINIMIDO)URONIUM TETRAFLUOROBORATE AS COUPLING REAGENT (VOL 10, PG 197, 1993), Glycoconjugate journal, 10(6), 1993, pp. 461-465
Citations number
23
Categorie Soggetti
Biology
Journal title
Glycoconjugate journal → ACNP
ISSN journal
02820080
Volume
10
Issue
6
Year of publication
1993
Pages
461 - 465
Database
ISI
SICI code
0282-0080(1993)10:6<461:SOOWOG>2.0.ZU;2-L
Abstract
Glycosides of glucose and lactose with di- and tetraethylene glycols, transformed into bifunctional (alcohol, ester) spacer molecules, have been synthesized. After deprotection, these spacer glycosides, contain ing a free carboxyl group, have been transformed efficiently into glyc oconjugates using N,N,N',N'-tetramethyl(succinimido)uronium tetrafluor oborate (TSTU) for the formation of an active ester.