RING TRANSFORMATIONS OF OXAZOLES AND THEIR DERIVATIVES - SYNTHESIS OFDIHYDRO-2-(2-HYDROXYPHENYLIMINO)-4-METHYLTHIAZOLES BY REACTION OF 2-(2-OXOPROPYLTHIO)BENZOXAZOLES WITH AMINES

Authors
KALCHEVA V TOSHEVA M HADJIEVA P
Citation
V. Kalcheva et al., RING TRANSFORMATIONS OF OXAZOLES AND THEIR DERIVATIVES - SYNTHESIS OFDIHYDRO-2-(2-HYDROXYPHENYLIMINO)-4-METHYLTHIAZOLES BY REACTION OF 2-(2-OXOPROPYLTHIO)BENZOXAZOLES WITH AMINES, Liebigs Annalen der Chemie, (12), 1993, pp. 1319-1322
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Liebigs Annalen der Chemie → ACNP
ISSN journal
01702041
Issue
12
Year of publication
1993
Pages
1319 - 1322
Database
ISI
SICI code
0170-2041(1993):12<1319:RTOOAT>2.0.ZU;2-Q
Abstract
Treatment of 2-(2-oxopropylthio)benzoxazoles 1a-d with an excess of pr imary amines in acetic acid or in perchloric acid affords 3-substitute d 2-(2-hydroxyphenylimino)-4-methylthiazoles 4a-q. Interaction of thia zoles 4a,i with diazomethane leads to the corresponding O-methyl deriv atives. The structure of compounds 4a-q is confirmed by an X-ray analy sis of compound 4d.