The work of Harper and subsequent authors has shown that finite sequen
ces (a(0),..., a(n)) arising from combinatorial problems are often suc
h that the polynomial A(z):=Sigma(k=0)(n) a(k)z(k) has only real zeros
. Basic examples include rows from the arrays of binomial coefficients
, Stirling numbers of the first and second kinds, and Eulerian numbers
. Assuming the a(k) are nonnegative, A(1)>0 and that A(z) is not const
ant, it is known that A(z) has only real zeros iff the normalized sequ
ence (a(0)/A(1),..., a(n)/A(1)) is the probability distribution of the
number of successes in n independent trials for some sequence of succ
ess probabilities. Such sequences (a(0),..., a(n)) are also known to b
e characterized by total positivity of the infinite matrix (a(i-j)) in
dexed by nonnegative integers i and j. This papers reviews inequalitie
s and approximations for such sequences, called Polya frequency sequen
ces which follow from their probabilistic representation. In combinato
rial examples these inequalities yield a number of improvements of kno
wn estimates. (C) 1997 Academic Press.