Cj. Lavie et al., BENEFITS OF CARDIAC REHABILITATION AND EXERCISE TRAINING IN SECONDARYCORONARY PREVENTION IN THE ELDERLY, Journal of the American College of Cardiology, 22(3), 1993, pp. 678-683
Objectives. The aim of this study was to determine the effects of card
iac rehabilitation and exercise training on plasma lipids, indexes of
obesity and exercise capacity in the elderly and to compare the benefi
ts in elderly patients with coronary heart disease with benefits in a
younger cohort. Background. Despite the well proved benefits of cardia
c rehabilitation and exercise training, elderly patients with coronary
heart disease are frequently not referred or vigorously encouraged to
pursue this therapy. In addition, only limited data are available for
these elderly patients on the benefits of cardiac rehabilitation on p
lasma lipids, indexes of obesity and exercise capacity. Methods. At tw
o large multispecialty teaching institutions, baseline and post-rehabi
litation data including plasma lipids, indexes of obesity and exercise
capacity were compared in 92 elderly patients (greater-than-or-equal-
to 65 years, mean age 70.1 +/- 4.1 years) and 182 younger patients (<6
5 years, mean 53.9 +/- 7.4 years) enrolled in phase II cardiac rehabil
itation and exercise programs after a major cardiac event. Results. At
baseline, body mass index (26.0 +/- 3.9 vs. 27.8 +/- 4.2 kg/M2, p < 0
.001), triglycerides (141 +/- 55 vs. 178 +/- 105 mg/dl, p < 0.01) and
estimated metabolic equivalents (METs) (5.6 +/- 1.6 vs. 7.7 +/- 3.0, p
< 0.0001) were lower and high density lipoprotein cholesterol was gre
ater (40.4 +/- 12.1 vs. 37.5 +/- 10.4 mg/dl, p < 0.05) in the elderly
than in younger patients. After rehabilitation, the elderly demonstrat
ed significant improvements in METs (5.6 +/- 1.6 vs. 7.5 +/- 2.3, p <
0.0001), body mass index (26.0 +/- 3.9 vs. 25.6 +/- 3.8 kg/m2, p < 0.0
1), percent body fat (24.4 +/- 7.0 vs. 22.9 +/- 7.2%, p < 0.0001), hig
h density lipoprotein cholesterol (40.4 +/- 12.1 vs. 43.0 +/- 11.4 mg/
dl, p < 0.001) and the ratio of low density to high density lipoprotei
n, cholesterol (3.6 +/- 1.3 vs. 3.3 +/- 1.0, p < 0.01) and a decrease
in triglycerides that approached statistical significance (141 +/- 55
vs. 130 +/- 76 mg/dl, p = 0.14) but not in total cholesterol or low de
nsity lipoprotein cholesterol. Improvements in functional capacity, pe
rcent body fat and body mass index, as well as lipids, were statistica
lly similar in the older and younger patients. Conclusions. Despite ba
seline differences, improvements in exercise capacity, obesity indexes
and lipids were very similar in older and younger patients enrolled i
n cardiac rehabilitation and exercise training. These data emphasize t
hat elderly patients should not be categorically denied the psychosoci
al, physical and risk factor benefits of secondary coronary prevention
including formal cardiac rehabilitation and supervised exercise train
ing.