INFLUENCE OF SPERMATOZOA CHARACTERISTICS ON GAMETE INTRAFALLOPIAN TRANSFER PROCEDURES - ANALYSIS OF RESULTS OBTAINED UTILIZING NORMOZOOSPERMIC, OLIGOASTHENOZOOSPERMIC AND DONOR SPERMATOZOA

The objective of this study was to analyse the efficacy of the gamete intra-Fallopian transfer (GIFT) procedure in relation to spermatozoa c haracteristics. A total of 268 infertile couples enlisted for GIFT wer e categorized into three groups on the basis of semen characteristics in the husband. These included oligoasthenozoospermic men in 88 retrie val cycles (group 1), normozoospermic men in 116 cycles (group 2) and azoospermic partners who needed donor semen in 86 cycles (group 3). Al l female patients had ovarian stimulation and laparoscopic GIFT. Pregn ancy rates were significantly higher with donor spermatozoa than with oligoasthenozoospermic or normozoospermic spermatozoa, i.e. 51.1% vers us 15.9% (P < 0.001), and 32.7% (P < 0.005). Implantation rates were s ignificantly higher with donor spermatozoa than with normo- or oligoas thenozoospermic spermatozoa (P < 0.01). These data suggest that GIFT d oes not give good results with male factor infertility. Donor cryopres erved semen gives higher pregnancy and implantation rates than normozo ospermic semen, and GIFT with donor spermatozoa gives a good chance of pregnancy to couples previously treated with artificial insemination using donor semen.