HUMAN INSULIN-LIKE GROWTH-FACTOR TYPE-I AND TYPE-II RECEPTORS ARE NETIMPRINTED

We have shown that the insulin-like growth factor type I and II recept ors are expressed equally from the maternal and paternal alleles in hu man tissues. The imprinting status of the type I insulin-like growth f actor receptor has not been reported while the type II receptor has pr eviously been shown to be maternally expressed in the mouse. That the imprinting of the insulin-like growth factor type II receptor is not c onserved between mouse and humans suggests that the physiological role of the IGF2 receptor may differ between these two species.